8005-8741 Screening compound: (2E)-N-(5-bromopyridin-2-yl)-3-phenylprop-2-enamide

8005-8741 Screening compound: (2E)-N-(5-bromopyridin-2-yl)-3-phenylprop-2-enamide
8005-8741 Screening compound: (2E)-N-(5-bromopyridin-2-yl)-3-phenylprop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8005-8741
(2E)-N-(5-bromopyridin-2-yl)-3-phenylprop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8005-8741

Molecular Formula

C14H11BrN2O (C14 H11 BrN2 O)

Compound Name

(2E)-N-(5-bromopyridin-2-yl)-3-phenylprop-2-enamide

IUPAC name

(2E)-N-(5-bromopyridin-2-yl)-3-phenylprop-2-enamide

SMILES

O=C(/C=C/c1ccccc1)Nc(cc1)ncc1Br

InChI

InChI=1S/C14H11BrN2O/c15-12-7-8-13(16-10-12)17-14(18)9-6-11-4-2-1-3-5-11/h1-10H,(H,16,17,18)

InChI Key

NFKCXWNXWWCWLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00469525

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

303.16

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.230

Distribution Coefficient, logD

4.218

Water Solubility, LogSw

-4.31

Polar Surface Area

32.821

Acid Dissociation Constant (pKa)

8.97

Base Dissociation Constant (pKb)

0.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8005-8741 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Human Receptors Annotated Library (5376 compounds)

KRAS-Targeted Library (16000 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8005-8741 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8005-8741?
Check Price and Availability of 8005-8741, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8005-8741 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8005-8741
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8005-8741
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8005-8741 available by request