8006-8146 Screening compound: 4-chloro-N-[(pyridin-3-yl)methyl]benzene-1-sulfonamide

8006-8146 Screening compound: 4-chloro-N-[(pyridin-3-yl)methyl]benzene-1-sulfonamide
8006-8146 Screening compound: 4-chloro-N-[(pyridin-3-yl)methyl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8006-8146
4-chloro-N-[(pyridin-3-yl)methyl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8006-8146

Molecular Formula

C12H11ClN2O2S (C12 H11 ClN2 O2 S)

Compound Name

4-chloro-N-[(pyridin-3-yl)methyl]benzene-1-sulfonamide

IUPAC name

4-chloro-N-[(pyridin-3-yl)methyl]benzene-1-sulfonamide

SMILES

O=S(c(cc1)ccc1Cl)(NCc1cnccc1)=O

InChI

InChI=1S/C12H11ClN2O2S/c13-11-3-5-12(6-4-11)18(16,17)15-9-10-2-1-7-14-8-10/h1-8,15H,9H2

InChI Key

RQLXDFUYSXYHQP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00826740

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

282.75

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.261

Distribution Coefficient, logD

2.260

Water Solubility, LogSw

-3.12

Polar Surface Area

51.515

Acid Dissociation Constant (pKa)

10.14

Base Dissociation Constant (pKb)

3.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

8006-8146 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Fragments Library (11262 compounds)

Glucocorticoid receptors Library (4806 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Nervous system
  • Cardiovascular
Structure:
  • Fragments
Targets:
  • Nuclear receptors
  • Others
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 8006-8146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8006-8146?
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What is the minimum amount of 8006-8146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8006-8146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8006-8146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8006-8146 available by request