8006-8659 Screening compound: 2-iodo-N-{4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide

8006-8659 Screening compound: 2-iodo-N-{4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide
8006-8659 Screening compound: 2-iodo-N-{4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8006-8659
2-iodo-N-{4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8006-8659

Molecular Formula

C18H15IN4O4S (C18 H15 IN4 O4 S)

Compound Name

2-iodo-N-{4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide

IUPAC name

2-iodo-N-{4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl}benzamide

SMILES

COc1cc(NS(c(cc2)ccc2NC(c(cccc2)c2I)=O)(=O)=O)ncn1

InChI

InChI=1S/C18H15IN4O4S/c1-27-17-10-16(20-11-21-17)23-28(25,26)13-8-6-12(7-9-13)22-18(24)14-4-2-3-5-15(14)19/h2-11H,1H3,(H,22,24)(H,20,21,23)

InChI Key

NIYQGBNSWMKUQI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00827122

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

510.31

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.939

Distribution Coefficient, logD

0.787

Water Solubility, LogSw

-3.85

Polar Surface Area

91.800

Acid Dissociation Constant (pKa)

5.25

Base Dissociation Constant (pKb)

1.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

8006-8659 in Drug Discovery

Included in Screening Libraries

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8006-8659 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8006-8659?
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What is the minimum amount of 8006-8659 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8006-8659
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8006-8659
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8006-8659 available by request