8007-0197 Screening compound: 2-cyclopropanecarbonyl-4-(4-fluorophenyl)-6-phenylthieno[2,3-b]pyridin-3-amine

8007-0197 Screening compound: 2-cyclopropanecarbonyl-4-(4-fluorophenyl)-6-phenylthieno[2,3-b]pyridin-3-amine
8007-0197 Screening compound: 2-cyclopropanecarbonyl-4-(4-fluorophenyl)-6-phenylthieno[2,3-b]pyridin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8007-0197
2-cyclopropanecarbonyl-4-(4-fluorophenyl)-6-phenylthieno[2,3-b]pyridin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8007-0197

Molecular Formula

C23H17FN2OS (C23 H17 FN2 OS)

Compound Name

2-cyclopropanecarbonyl-4-(4-fluorophenyl)-6-phenylthieno[2,3-b]pyridin-3-amine

IUPAC name

2-cyclopropanecarbonyl-4-(4-fluorophenyl)-6-phenylthieno[23-b]pyridin-3-amine

SMILES

Nc1c(C(C2CC2)=O)sc2nc(-c3ccccc3)cc(-c(cc3)ccc3F)c12

InChI

InChI=1S/C23H17FN2OS/c24-16-10-8-13(9-11-16)17-12-18(14-4-2-1-3-5-14)26-23-19(17)20(25)22(28-23)21(27)15-6-7-15/h1-5,8-12,15H,6-7,25H2

InChI Key

RUIGQPSTGMZMEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00827888

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.47

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.375

Distribution Coefficient, logD

6.373

Water Solubility, LogSw

-6.34

Polar Surface Area

42.792

Acid Dissociation Constant (pKa)

17.95

Base Dissociation Constant (pKb)

5.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

8007-0197 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8007-0197 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8007-0197?
Check Price and Availability of 8007-0197, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8007-0197 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8007-0197
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8007-0197
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8007-0197 available by request