8008-2756 Screening compound: N-[(E)-1-(2,4-dichlorophenyl)methylidene]-N-[4-(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)phenyl]amine

8008-2756 Screening compound: N-[(E)-1-(2,4-dichlorophenyl)methylidene]-N-[4-(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)phenyl]amine
8008-2756 Screening compound: N-[(E)-1-(2,4-dichlorophenyl)methylidene]-N-[4-(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)phenyl]amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8008-2756
N-[(E)-1-(2,4-dichlorophenyl)methylidene]-N-[4-(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)phenyl]amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8008-2756

Molecular Formula

C26H22Cl2N2 (C26 H22 Cl2 N2)

Compound Name

N-[(E)-1-(2,4-dichlorophenyl)methylidene]-N-[4-(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)phenyl]amine

IUPAC name

(E)-1-(24-dichlorophenyl)-N-(4-{8-methyl-3H3aH4H5H9bH-cyclopenta[c]quinolin-4-yl}phenyl)methanimine

SMILES

Cc(cc1)cc(C2C=CCC22)c1NC2c(cc1)ccc1/N=C/c(ccc(Cl)c1)c1Cl

InChI

InChI=1S/C26H22Cl2N2/c1-16-5-12-25-23(13-16)21-3-2-4-22(21)26(30-25)17-7-10-20(11-8-17)29-15-18-6-9-19(27)14-24(18)28/h2-3,5-15,21-22,26,30H,4H2,1H3

InChI Key

JAHNEERZSBIKFN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01208391

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.38

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

7.775

Distribution Coefficient, logD

7.775

Water Solubility, LogSw

-6.76

Polar Surface Area

20.449

Acid Dissociation Constant (pKa)

16.95

Base Dissociation Constant (pKb)

4.68

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

19.23

8008-2756 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8008-2756 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8008-2756?
Check Price and Availability of 8008-2756, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8008-2756 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8008-2756
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8008-2756
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8008-2756 available by request