8009-7848 Screening compound: N~1~-(9H-fluoren-2-yl)-3-[2-(1-hydroxycyclohexyl)-1-ethynyl]benzamide

8009-7848 Screening compound: N~1~-(9H-fluoren-2-yl)-3-[2-(1-hydroxycyclohexyl)-1-ethynyl]benzamide
8009-7848 Screening compound: N~1~-(9H-fluoren-2-yl)-3-[2-(1-hydroxycyclohexyl)-1-ethynyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8009-7848
N~1~-(9H-fluoren-2-yl)-3-[2-(1-hydroxycyclohexyl)-1-ethynyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8009-7848

Molecular Formula

C28H25NO2 (C28 H25 NO2)

Compound Name

N~1~-(9H-fluoren-2-yl)-3-[2-(1-hydroxycyclohexyl)-1-ethynyl]benzamide

IUPAC name

N-(9H-fluoren-2-yl)-3-[2-(1-hydroxycyclohexyl)ethynyl]benzamide

SMILES

OC1(CCCCC1)C#Cc1cccc(C(Nc(cc2)cc(C3)c2-c2c3cccc2)=O)c1

InChI

InChI=1S/C28H25NO2/c30-27(22-9-6-7-20(17-22)13-16-28(31)14-4-1-5-15-28)29-24-11-12-26-23(19-24)18-21-8-2-3-10-25(21)26/h2-3,6-12,17,19,31H,1,4-5,14-15,18H2,(H,29,30)

InChI Key

QCUKRLIGEBLXTB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01820290

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.51

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.711

Distribution Coefficient, logD

6.711

Water Solubility, LogSw

-5.94

Polar Surface Area

38.838

Acid Dissociation Constant (pKa)

11.43

Base Dissociation Constant (pKb)

-4.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

8009-7848 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Lipid Metabolism Library (9174 compounds)

Regenerative Medicine Focused Library (23016 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 8009-7848 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8009-7848?
Check Price and Availability of 8009-7848, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8009-7848 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8009-7848
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8009-7848
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8009-7848 available by request