8010-0306 Screening compound: 4-(4-chlorophenyl)-2-(3-phenylpyrrolidin-1-yl)-1,3-thiazole

8010-0306 Screening compound: 4-(4-chlorophenyl)-2-(3-phenylpyrrolidin-1-yl)-1,3-thiazole
8010-0306 Screening compound: 4-(4-chlorophenyl)-2-(3-phenylpyrrolidin-1-yl)-1,3-thiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-0306
4-(4-chlorophenyl)-2-(3-phenylpyrrolidin-1-yl)-1,3-thiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-0306

Molecular Formula

C19H17ClN2S (C19 H17 ClN2 S)

Compound Name

4-(4-chlorophenyl)-2-(3-phenylpyrrolidin-1-yl)-1,3-thiazole

IUPAC name

4-(4-chlorophenyl)-2-(3-phenylpyrrolidin-1-yl)-13-thiazole

SMILES

Clc(cc1)ccc1-c1csc(N(CC2)CC2c2ccccc2)n1

InChI

InChI=1S/C19H17ClN2S/c20-17-8-6-15(7-9-17)18-13-23-19(21-18)22-11-10-16(12-22)14-4-2-1-3-5-14/h1-9,13,16H,10-12H2/t16-/m1/s1

InChI Key

RJJPDKWWEKHSDV-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD01896131

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.88

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

6.486

Distribution Coefficient, logD

6.486

Water Solubility, LogSw

-6.80

Polar Surface Area

13.268

Acid Dissociation Constant (pKa)

19.38

Base Dissociation Constant (pKb)

1.72

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.10

8010-0306 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

GPCR Targeted Library (31838 compounds)

Human Receptors Annotated Library (5376 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 8010-0306 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-0306?
Check Price and Availability of 8010-0306, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8010-0306 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-0306
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-0306
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-0306 available by request