8010-0352 Screening compound: 6-amino-3-(tert-butyl)-4-(4-ethylphenyl)-1,4-dihydropyrano[2,3-c]pyrazol-5-yl cyanide

8010-0352 Screening compound: 6-amino-3-(tert-butyl)-4-(4-ethylphenyl)-1,4-dihydropyrano[2,3-c]pyrazol-5-yl cyanide
8010-0352 Screening compound: 6-amino-3-(tert-butyl)-4-(4-ethylphenyl)-1,4-dihydropyrano[2,3-c]pyrazol-5-yl cyanide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-0352
6-amino-3-(tert-butyl)-4-(4-ethylphenyl)-1,4-dihydropyrano[2,3-c]pyrazol-5-yl cyanide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-0352

Molecular Formula

C19H22N4O (C19 H22 N4 O)

Compound Name

6-amino-3-(tert-butyl)-4-(4-ethylphenyl)-1,4-dihydropyrano[2,3-c]pyrazol-5-yl cyanide

IUPAC name

6-amino-3-tert-butyl-4-(4-ethylphenyl)-1H4H-pyrano[23-c]pyrazole-5-carbonitrile

SMILES

CCc1ccc(C2C(C#N)=C(N)Oc3c2c(C(C)(C)C)n[nH]3)cc1

InChI

InChI=1S/C19H22N4O/c1-5-11-6-8-12(9-7-11)14-13(10-20)17(21)24-18-15(14)16(22-23-18)19(2,3)4/h6-9,14H,5,21H2,1-4H3,(H,22,23)/t14-/m1/s1

InChI Key

QAWRWNYZUXEITP-CQSZACIVSA-N

MDL Number (MFCD)

MFCD01926211

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.41

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.753

Distribution Coefficient, logD

3.753

Water Solubility, LogSw

-4.18

Polar Surface Area

70.745

Acid Dissociation Constant (pKa)

13.78

Base Dissociation Constant (pKb)

0.33

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.84

8010-0352 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8010-0352 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-0352?
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What is the minimum amount of 8010-0352 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-0352
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-0352
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-0352 available by request