8010-0641 Screening compound: 5-(2,5-dimethylphenyl)-3-[(5E)-5H-indeno[1,2-b]pyridin-5-ylidene]-2,3-dihydrofuran-2-one

8010-0641 Screening compound: 5-(2,5-dimethylphenyl)-3-[(5E)-5H-indeno[1,2-b]pyridin-5-ylidene]-2,3-dihydrofuran-2-one
8010-0641 Screening compound: 5-(2,5-dimethylphenyl)-3-[(5E)-5H-indeno[1,2-b]pyridin-5-ylidene]-2,3-dihydrofuran-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-0641
5-(2,5-dimethylphenyl)-3-[(5E)-5H-indeno[1,2-b]pyridin-5-ylidene]-2,3-dihydrofuran-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-0641

Molecular Formula

C24H17NO2 (C24 H17 NO2)

Compound Name

5-(2,5-dimethylphenyl)-3-[(5E)-5H-indeno[1,2-b]pyridin-5-ylidene]-2,3-dihydrofuran-2-one

IUPAC name

5-(25-dimethylphenyl)-3-[(5E)-5H-indeno[12-b]pyridin-5-ylidene]-23-dihydrofuran-2-one

SMILES

Cc1cc(C(OC2=O)=C/C2=C(/c2c-3cccc2)\c2c3nccc2)c(C)cc1

InChI

InChI=1S/C24H17NO2/c1-14-9-10-15(2)19(12-14)21-13-20(24(26)27-21)22-16-6-3-4-7-17(16)23-18(22)8-5-11-25-23/h3-13H,1-2H3

InChI Key

TVOCLYXRJGHBCC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01870957

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.753

Distribution Coefficient, logD

4.753

Water Solubility, LogSw

-4.59

Polar Surface Area

32.664

Acid Dissociation Constant (pKa)

27.63

Base Dissociation Constant (pKb)

-5.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

8010-0641 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8010-0641 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-0641?
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What is the minimum amount of 8010-0641 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-0641
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-0641
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-0641 available by request