8010-1564 Screening compound: methyl 2-(5-bromo-2-chlorobenzamido)-4-methyl-1,3-thiazole-5-carboxylate

8010-1564 Screening compound: methyl 2-(5-bromo-2-chlorobenzamido)-4-methyl-1,3-thiazole-5-carboxylate
8010-1564 Screening compound: methyl 2-(5-bromo-2-chlorobenzamido)-4-methyl-1,3-thiazole-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-1564
methyl 2-(5-bromo-2-chlorobenzamido)-4-methyl-1,3-thiazole-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-1564

Molecular Formula

C13H10BrClN2O3S (C13 H10 BrClN2 O3 S)

Compound Name

methyl 2-(5-bromo-2-chlorobenzamido)-4-methyl-1,3-thiazole-5-carboxylate

IUPAC name

methyl 2-(5-bromo-2-chlorobenzamido)-4-methyl-13-thiazole-5-carboxylate

SMILES

Cc1c(C(OC)=O)sc(NC(c(cc(cc2)Br)c2Cl)=O)n1

InChI

InChI=1S/C13H10BrClN2O3S/c1-6-10(12(19)20-2)21-13(16-6)17-11(18)8-5-7(14)3-4-9(8)15/h3-5H,1-2H3,(H,16,17,18)

InChI Key

RTWXCWDYTJWFFS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01840882

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.66

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.250

Distribution Coefficient, logD

1.813

Water Solubility, LogSw

-4.59

Polar Surface Area

55.127

Acid Dissociation Constant (pKa)

4.96

Base Dissociation Constant (pKb)

0.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.40

8010-1564 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

SH2 Library (10483 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 8010-1564 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-1564?
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What is the minimum amount of 8010-1564 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-1564
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-1564
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-1564 available by request