8010-5644 Screening compound: 2-(phenylsulfonyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine

8010-5644 Screening compound: 2-(phenylsulfonyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine
8010-5644 Screening compound: 2-(phenylsulfonyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-5644
2-(phenylsulfonyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-5644

Molecular Formula

C18H11F3N2O2S3 (C18 H11 F3 N2 O2 S3)

Compound Name

2-(phenylsulfonyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine

IUPAC name

2-(benzenesulfonyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[23-b]pyridin-3-amine

SMILES

Nc(c(c(C(F)(F)F)cc(-c1cccs1)n1)c1s1)c1S(c1ccccc1)(=O)=O

InChI

InChI=1S/C18H11F3N2O2S3/c19-18(20,21)11-9-12(13-7-4-8-26-13)23-16-14(11)15(22)17(27-16)28(24,25)10-5-2-1-3-6-10/h1-9H,22H2

InChI Key

RWEBUXJRSURQDH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02110693

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.536

Distribution Coefficient, logD

5.536

Water Solubility, LogSw

-6.21

Polar Surface Area

59.593

Acid Dissociation Constant (pKa)

16.63

Base Dissociation Constant (pKb)

2.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.56

8010-5644 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with 8010-5644 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-5644?
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What is the minimum amount of 8010-5644 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-5644
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-5644
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-5644 available by request