8010-7819 Screening compound: 5-(2,4-dichlorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-(3-pyridylmethyl)-1,5-dihydro-2H-pyrrol-2-one

8010-7819 Screening compound: 5-(2,4-dichlorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-(3-pyridylmethyl)-1,5-dihydro-2H-pyrrol-2-one
8010-7819 Screening compound: 5-(2,4-dichlorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-(3-pyridylmethyl)-1,5-dihydro-2H-pyrrol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-7819
5-(2,4-dichlorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-(3-pyridylmethyl)-1,5-dihydro-2H-pyrrol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-7819

Molecular Formula

C24H18Cl2N2O3 (C24 H18 Cl2 N2 O3)

Compound Name

5-(2,4-dichlorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-(3-pyridylmethyl)-1,5-dihydro-2H-pyrrol-2-one

IUPAC name

5-(24-dichlorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-[(pyridin-3-yl)methyl]-25-dihydro-1H-pyrrol-2-one

SMILES

Cc(cc1)ccc1C(C(C(c(ccc(Cl)c1)c1Cl)N(Cc1cnccc1)C1=O)=C1O)=O

InChI

InChI=1S/C24H18Cl2N2O3/c1-14-4-6-16(7-5-14)22(29)20-21(18-9-8-17(25)11-19(18)26)28(24(31)23(20)30)13-15-3-2-10-27-12-15/h2-12,21,30H,13H2,1H3/t21-/m1/s1

InChI Key

FXWQQHZLRBNDDN-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD02647216

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.32

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.599

Distribution Coefficient, logD

4.596

Water Solubility, LogSw

-4.47

Polar Surface Area

54.345

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

2.73

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

8010-7819 in Drug Discovery

Included in Screening Libraries

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with 8010-7819 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-7819?
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What is the minimum amount of 8010-7819 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-7819
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-7819
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-7819 available by request