8012-1480 Screening compound: 3'-benzyl-5-methoxy-1,2,3',4'-tetrahydro-1'H-spiro[indole-3,2'-quinazoline]-2,4'-dione

8012-1480 Screening compound: 3'-benzyl-5-methoxy-1,2,3',4'-tetrahydro-1'H-spiro[indole-3,2'-quinazoline]-2,4'-dione
8012-1480 Screening compound: 3'-benzyl-5-methoxy-1,2,3',4'-tetrahydro-1'H-spiro[indole-3,2'-quinazoline]-2,4'-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 8012-1480
3'-benzyl-5-methoxy-1,2,3',4'-tetrahydro-1'H-spiro[indole-3,2'-quinazoline]-2,4'-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8012-1480

Molecular Formula

C23H19N3O3 (C23 H19 N3 O3)

Compound Name

3'-benzyl-5-methoxy-1,2,3',4'-tetrahydro-1'H-spiro[indole-3,2'-quinazoline]-2,4'-dione

IUPAC name

3'-benzyl-5-methoxy-123'4'-tetrahydro-1'H-spiro[indole-32'-quinazoline]-24'-dione

SMILES

COc(cc1)cc(C2(Nc3c4cccc3)N(Cc3ccccc3)C4=O)c1NC2=O

InChI

InChI=1S/C23H19N3O3/c1-29-16-11-12-20-18(13-16)23(22(28)24-20)25-19-10-6-5-9-17(19)21(27)26(23)14-15-7-3-2-4-8-15/h2-13,25H,14H2,1H3,(H,24,28)/t23-/m0/s1

InChI Key

JUXBJWICEBSJGU-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD03067047

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.305

Distribution Coefficient, logD

4.304

Water Solubility, LogSw

-4.42

Polar Surface Area

59.967

Acid Dissociation Constant (pKa)

11.20

Base Dissociation Constant (pKb)

1.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.04

8012-1480 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Antiviral Library (67538 compounds)

KRAS-Targeted Library (16000 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Antibacterial Compounds Library (13827 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Immune system
  • animal
  • Cancer
Agro:
  • Agro
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with 8012-1480 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8012-1480?
Check Price and Availability of 8012-1480, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8012-1480 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8012-1480
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8012-1480
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8012-1480 available by request