8012-2237 Screening compound: 4-{[(4,5-diphenyl-1,3-oxazol-2-yl)sulfanyl]methyl}-6-morpholino-1,3,5-triazin-2-amine

8012-2237 Screening compound: 4-{[(4,5-diphenyl-1,3-oxazol-2-yl)sulfanyl]methyl}-6-morpholino-1,3,5-triazin-2-amine
8012-2237 Screening compound: 4-{[(4,5-diphenyl-1,3-oxazol-2-yl)sulfanyl]methyl}-6-morpholino-1,3,5-triazin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8012-2237
4-{[(4,5-diphenyl-1,3-oxazol-2-yl)sulfanyl]methyl}-6-morpholino-1,3,5-triazin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8012-2237

Molecular Formula

C23H22N6O2S (C23 H22 N6 O2 S)

Compound Name

4-{[(4,5-diphenyl-1,3-oxazol-2-yl)sulfanyl]methyl}-6-morpholino-1,3,5-triazin-2-amine

IUPAC name

4-{[(45-diphenyl-13-oxazol-2-yl)sulfanyl]methyl}-6-(morpholin-4-yl)-135-triazin-2-amine

SMILES

Nc1nc(CSc2nc(-c3ccccc3)c(-c3ccccc3)o2)nc(N2CCOCC2)n1

InChI

InChI=1S/C23H22N6O2S/c24-21-25-18(26-22(28-21)29-11-13-30-14-12-29)15-32-23-27-19(16-7-3-1-4-8-16)20(31-23)17-9-5-2-6-10-17/h1-10H,11-15H2,(H2,24,25,26,28)

InChI Key

XXJXKVSTNSVABS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03035760

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.566

Distribution Coefficient, logD

4.566

Water Solubility, LogSw

-4.52

Polar Surface Area

79.093

Acid Dissociation Constant (pKa)

17.34

Base Dissociation Constant (pKb)

2.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.74

8012-2237 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8012-2237 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8012-2237?
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What is the minimum amount of 8012-2237 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8012-2237
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8012-2237
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8012-2237 available by request