8012-7143 Screening compound: N-(4-cyclopropyl-1,3-thiazol-2-yl)-6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)hexanamide

8012-7143 Screening compound: N-(4-cyclopropyl-1,3-thiazol-2-yl)-6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)hexanamide
8012-7143 Screening compound: N-(4-cyclopropyl-1,3-thiazol-2-yl)-6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)hexanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8012-7143
N-(4-cyclopropyl-1,3-thiazol-2-yl)-6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)hexanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8012-7143

Molecular Formula

C20H21N3O3S (C20 H21 N3 O3 S)

Compound Name

N-(4-cyclopropyl-1,3-thiazol-2-yl)-6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)hexanamide

IUPAC name

N-(4-cyclopropyl-13-thiazol-2-yl)-6-(13-dioxo-23-dihydro-1H-isoindol-2-yl)hexanamide

SMILES

O=C(CCCCCN(C(c1c2cccc1)=O)C2=O)Nc1nc(C2CC2)cs1

InChI

InChI=1S/C20H21N3O3S/c24-17(22-20-21-16(12-27-20)13-9-10-13)8-2-1-5-11-23-18(25)14-6-3-4-7-15(14)19(23)26/h3-4,6-7,12-13H,1-2,5,8-11H2,(H,21,22,24)

InChI Key

SZXBGJLUVVRHNN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03034906

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.480

Distribution Coefficient, logD

3.469

Water Solubility, LogSw

-3.73

Polar Surface Area

62.917

Acid Dissociation Constant (pKa)

9.01

Base Dissociation Constant (pKb)

3.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

8012-7143 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8012-7143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8012-7143?
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What is the minimum amount of 8012-7143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8012-7143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8012-7143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8012-7143 available by request