8013-0177 Screening compound: 7-(chlorodifluoromethyl)-5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

8013-0177 Screening compound: 7-(chlorodifluoromethyl)-5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
8013-0177 Screening compound: 7-(chlorodifluoromethyl)-5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8013-0177
7-(chlorodifluoromethyl)-5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8013-0177

Molecular Formula

C18H15ClF2N6O2 (C18 H15 ClF2 N6 O2)

Compound Name

7-(chlorodifluoromethyl)-5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

7-(chlorodifluoromethyl)-5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

O=C(c1nn2c(C(F)(F)Cl)cc(-c3ccco3)nc2c1)NCCCn1cncc1

InChI

InChI=1S/C18H15ClF2N6O2/c19-18(20,21)15-9-12(14-3-1-8-29-14)24-16-10-13(25-27(15)16)17(28)23-4-2-6-26-7-5-22-11-26/h1,3,5,7-11H,2,4,6H2,(H,23,28)

InChI Key

NJEVJIRIMUUONB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03408323

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

420.81

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.367

Distribution Coefficient, logD

2.125

Water Solubility, LogSw

-3.45

Polar Surface Area

64.031

Acid Dissociation Constant (pKa)

14.74

Base Dissociation Constant (pKb)

7.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

8013-0177 in Drug Discovery

Included in Screening Libraries

Anti-HIV1 Library (19540 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 8013-0177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8013-0177?
Check Price and Availability of 8013-0177, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8013-0177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8013-0177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8013-0177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8013-0177 available by request