8014-1448 Screening compound: 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(4-acetamido-1,2,5-oxadiazol-3-yl)acetamide

8014-1448 Screening compound: 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(4-acetamido-1,2,5-oxadiazol-3-yl)acetamide
8014-1448 Screening compound: 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(4-acetamido-1,2,5-oxadiazol-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8014-1448
2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(4-acetamido-1,2,5-oxadiazol-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8014-1448

Molecular Formula

C8H9N7O3S2 (C8 H9 N7 O3 S2)

Compound Name

2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(4-acetamido-1,2,5-oxadiazol-3-yl)acetamide

IUPAC name

2-[(5-amino-134-thiadiazol-2-yl)sulfanyl]-N-(4-acetamido-125-oxadiazol-3-yl)acetamide

SMILES

CC(Nc1nonc1NC(CSc1nnc(N)s1)=O)=O

InChI

InChI=1S/C8H9N7O3S2/c1-3(16)10-5-6(15-18-14-5)11-4(17)2-19-8-13-12-7(9)20-8/h2H2,1H3,(H2,9,12)(H,10,14,16)(H,11,15,17)

InChI Key

HNIGDWIGKGXYBS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02906268

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

315.34

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

-0.159

Distribution Coefficient, logD

-1.848

Water Solubility, LogSw

-1.57

Polar Surface Area

126.938

Acid Dissociation Constant (pKa)

5.72

Base Dissociation Constant (pKb)

-0.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

8014-1448 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8014-1448 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8014-1448?
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What is the minimum amount of 8014-1448 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8014-1448
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8014-1448
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8014-1448 available by request