8014-7690 Screening compound: 4-(3,4-dimethoxyphenyl)-1-(2,5-dimethylphenyl)-3-(4-methoxyphenoxy)azetidin-2-one

8014-7690 Screening compound: 4-(3,4-dimethoxyphenyl)-1-(2,5-dimethylphenyl)-3-(4-methoxyphenoxy)azetidin-2-one
8014-7690 Screening compound: 4-(3,4-dimethoxyphenyl)-1-(2,5-dimethylphenyl)-3-(4-methoxyphenoxy)azetidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8014-7690
4-(3,4-dimethoxyphenyl)-1-(2,5-dimethylphenyl)-3-(4-methoxyphenoxy)azetidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8014-7690

Molecular Formula

C26H27NO5 (C26 H27 NO5)

Compound Name

4-(3,4-dimethoxyphenyl)-1-(2,5-dimethylphenyl)-3-(4-methoxyphenoxy)azetidin-2-one

IUPAC name

4-(34-dimethoxyphenyl)-1-(25-dimethylphenyl)-3-(4-methoxyphenoxy)azetidin-2-one

SMILES

Cc1cc(N(C(C2Oc(cc3)ccc3OC)c(cc3)cc(OC)c3OC)C2=O)c(C)cc1

InChI

InChI=1S/C26H27NO5/c1-16-6-7-17(2)21(14-16)27-24(18-8-13-22(30-4)23(15-18)31-5)25(26(27)28)32-20-11-9-19(29-3)10-12-20/h6-15,24-25H,1-5H3

InChI Key

XUJZOPWPXQIPOU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03632661

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.837

Distribution Coefficient, logD

4.837

Water Solubility, LogSw

-4.76

Polar Surface Area

44.294

Acid Dissociation Constant (pKa)

19.75

Base Dissociation Constant (pKb)

-0.79

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

26.92

8014-7690 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antimitotic Tubulin Library (17355 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with 8014-7690 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8014-7690?
Check Price and Availability of 8014-7690, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8014-7690 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8014-7690
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8014-7690
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8014-7690 available by request