8014-9180 Screening compound: N-(diphenylmethyl)-2-(1H-indol-3-yl)-2-oxoacetamide

8014-9180 Screening compound: N-(diphenylmethyl)-2-(1H-indol-3-yl)-2-oxoacetamide
8014-9180 Screening compound: N-(diphenylmethyl)-2-(1H-indol-3-yl)-2-oxoacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8014-9180
N-(diphenylmethyl)-2-(1H-indol-3-yl)-2-oxoacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8014-9180

Molecular Formula

C23H18N2O2 (C23 H18 N2 O2)

Compound Name

N-(diphenylmethyl)-2-(1H-indol-3-yl)-2-oxoacetamide

IUPAC name

N-(diphenylmethyl)-2-(1H-indol-3-yl)-2-oxoacetamide

SMILES

O=C(C(NC(c1ccccc1)c1ccccc1)=O)c1c[nH]c2c1cccc2

InChI

InChI=1S/C23H18N2O2/c26-22(19-15-24-20-14-8-7-13-18(19)20)23(27)25-21(16-9-3-1-4-10-16)17-11-5-2-6-12-17/h1-15,21,24H,(H,25,27)

InChI Key

JLQCJIRILUPPPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00569208

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.439

Distribution Coefficient, logD

4.423

Water Solubility, LogSw

-4.52

Polar Surface Area

47.342

Acid Dissociation Constant (pKa)

8.82

Base Dissociation Constant (pKb)

-2.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

8014-9180 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Covalent Inhibitors Library (7986 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with 8014-9180 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8014-9180?
Check Price and Availability of 8014-9180, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8014-9180 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8014-9180
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8014-9180
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8014-9180 available by request