8015-2508 Screening compound: 4-{4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperazin-1-yl}-2-methylquinoline

8015-2508 Screening compound: 4-{4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperazin-1-yl}-2-methylquinoline
8015-2508 Screening compound: 4-{4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperazin-1-yl}-2-methylquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound 8015-2508
4-{4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperazin-1-yl}-2-methylquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8015-2508

Molecular Formula

C24H24N4OS (C24 H24 N4 OS)

Compound Name

4-{4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]piperazin-1-yl}-2-methylquinoline

IUPAC name

4-{4-[4-(4-methoxyphenyl)-13-thiazol-2-yl]piperazin-1-yl}-2-methylquinoline

SMILES

Cc1nc2ccccc2c(N(CC2)CCN2c2nc(-c(cc3)ccc3OC)cs2)c1

InChI

InChI=1S/C24H24N4OS/c1-17-15-23(20-5-3-4-6-21(20)25-17)27-11-13-28(14-12-27)24-26-22(16-30-24)18-7-9-19(29-2)10-8-18/h3-10,15-16H,11-14H2,1-2H3

InChI Key

KOPSXLCFXMEYHM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03856337

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.55

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.877

Distribution Coefficient, logD

3.818

Water Solubility, LogSw

-5.82

Polar Surface Area

31.880

Acid Dissociation Constant (pKa)

23.11

Base Dissociation Constant (pKb)

9.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

8015-2508 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with 8015-2508 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8015-2508?
Check Price and Availability of 8015-2508, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8015-2508 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8015-2508
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8015-2508
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8015-2508 available by request