8015-3652 Screening compound: N-{3-[(3-cyano-4,6-dimethylpyridin-2-yl)oxy]phenyl}naphthalene-2-sulfonamide

8015-3652 Screening compound: N-{3-[(3-cyano-4,6-dimethylpyridin-2-yl)oxy]phenyl}naphthalene-2-sulfonamide
8015-3652 Screening compound: N-{3-[(3-cyano-4,6-dimethylpyridin-2-yl)oxy]phenyl}naphthalene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8015-3652
N-{3-[(3-cyano-4,6-dimethylpyridin-2-yl)oxy]phenyl}naphthalene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8015-3652

Molecular Formula

C24H19N3O3S (C24 H19 N3 O3 S)

Compound Name

N-{3-[(3-cyano-4,6-dimethylpyridin-2-yl)oxy]phenyl}naphthalene-2-sulfonamide

IUPAC name

N-{3-[(3-cyano-46-dimethylpyridin-2-yl)oxy]phenyl}naphthalene-2-sulfonamide

SMILES

Cc(cc(C)nc1Oc2cccc(NS(c3cc4ccccc4cc3)(=O)=O)c2)c1C#N

InChI

InChI=1S/C24H19N3O3S/c1-16-12-17(2)26-24(23(16)15-25)30-21-9-5-8-20(14-21)27-31(28,29)22-11-10-18-6-3-4-7-19(18)13-22/h3-14,27H,1-2H3

InChI Key

PKJKYYBQYAYJRF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04060989

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.166

Distribution Coefficient, logD

5.091

Water Solubility, LogSw

-5.98

Polar Surface Area

73.600

Acid Dissociation Constant (pKa)

8.13

Base Dissociation Constant (pKb)

0.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

8015-3652 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8015-3652 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8015-3652?
Check Price and Availability of 8015-3652, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8015-3652 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8015-3652
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8015-3652
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8015-3652 available by request