8018-0378 Screening compound: 1-hydroxy-N-(pyridin-2-yl)naphthalene-2-carboxamide

8018-0378 Screening compound: 1-hydroxy-N-(pyridin-2-yl)naphthalene-2-carboxamide
8018-0378 Screening compound: 1-hydroxy-N-(pyridin-2-yl)naphthalene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-0378
1-hydroxy-N-(pyridin-2-yl)naphthalene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-0378

Molecular Formula

C16H12N2O2 (C16 H12 N2 O2)

Compound Name

1-hydroxy-N-(pyridin-2-yl)naphthalene-2-carboxamide

IUPAC name

1-hydroxy-N-(pyridin-2-yl)naphthalene-2-carboxamide

SMILES

Oc(c1ccccc1cc1)c1C(Nc1ncccc1)=O

InChI

InChI=1S/C16H12N2O2/c19-15-12-6-2-1-5-11(12)8-9-13(15)16(20)18-14-7-3-4-10-17-14/h1-10,19H,(H,17,18,20)

InChI Key

AHDNTEHUSMILBP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07022077

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

264.28

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.491

Distribution Coefficient, logD

3.380

Water Solubility, LogSw

-3.53

Polar Surface Area

48.152

Acid Dissociation Constant (pKa)

7.93

Base Dissociation Constant (pKb)

3.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8018-0378 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Human Receptors Annotated Library (5376 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Proteases
  • Proteases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8018-0378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-0378?
Check Price and Availability of 8018-0378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-0378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-0378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-0378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-0378 available by request