8018-0975 Screening compound: 2-[(3-chlorophenyl)amino]-5,7-dihydroxythieno[3,2-b]pyridine-3-carbonitrile

8018-0975 Screening compound: 2-[(3-chlorophenyl)amino]-5,7-dihydroxythieno[3,2-b]pyridine-3-carbonitrile
8018-0975 Screening compound: 2-[(3-chlorophenyl)amino]-5,7-dihydroxythieno[3,2-b]pyridine-3-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-0975
2-[(3-chlorophenyl)amino]-5,7-dihydroxythieno[3,2-b]pyridine-3-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-0975

Molecular Formula

C14H8ClN3O2S (C14 H8 ClN3 O2 S)

Compound Name

2-[(3-chlorophenyl)amino]-5,7-dihydroxythieno[3,2-b]pyridine-3-carbonitrile

IUPAC name

2-[(3-chlorophenyl)amino]-57-dihydroxythieno[32-b]pyridine-3-carbonitrile

SMILES

N#Cc1c(Nc2cccc(Cl)c2)sc(c(O)c2)c1nc2O

InChI

InChI=1S/C14H8ClN3O2S/c15-7-2-1-3-8(4-7)17-14-9(6-16)12-13(21-14)10(19)5-11(20)18-12/h1-5,17H,(H2,18,19,20)

InChI Key

PVUNIVFIMZWLRV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07022543

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

317.76

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.613

Distribution Coefficient, logD

2.218

Water Solubility, LogSw

-3.91

Polar Surface Area

68.910

Acid Dissociation Constant (pKa)

6.02

Base Dissociation Constant (pKb)

-0.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8018-0975 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Human Proteases Annotated Library (2868 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8018-0975 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-0975?
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What is the minimum amount of 8018-0975 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-0975
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-0975
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-0975 available by request