8018-1134 Screening compound: 2-(2-{[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]methyl}-1H-1,3-benzimidazol-1-yl)acetamide

8018-1134 Screening compound: 2-(2-{[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]methyl}-1H-1,3-benzimidazol-1-yl)acetamide
8018-1134 Screening compound: 2-(2-{[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]methyl}-1H-1,3-benzimidazol-1-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-1134
2-(2-{[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]methyl}-1H-1,3-benzimidazol-1-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-1134

Molecular Formula

C18H14F3N5O (C18 H14 F3 N5 O)

Compound Name

2-(2-{[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]methyl}-1H-1,3-benzimidazol-1-yl)acetamide

IUPAC name

2-(2-{[2-(trifluoromethyl)-1H-13-benzodiazol-1-yl]methyl}-1H-13-benzodiazol-1-yl)acetamide

SMILES

NC(Cn1c(cccc2)c2nc1Cn1c(cccc2)c2nc1C(F)(F)F)=O

InChI

InChI=1S/C18H14F3N5O/c19-18(20,21)17-24-12-6-2-4-8-14(12)26(17)10-16-23-11-5-1-3-7-13(11)25(16)9-15(22)27/h1-8H,9-10H2,(H2,22,27)

InChI Key

OHVZPABYOJGHSR-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.34

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.045

Distribution Coefficient, logD

3.043

Water Solubility, LogSw

-3.09

Polar Surface Area

54.731

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

5.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.67

8018-1134 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 8018-1134 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-1134?
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What is the minimum amount of 8018-1134 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-1134
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-1134
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-1134 available by request