8018-1614 Screening compound: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-{1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide

8018-1614 Screening compound: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-{1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide
8018-1614 Screening compound: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-{1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-1614
N-[2-chloro-5-(trifluoromethyl)phenyl]-2-{1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-1614

Molecular Formula

C24H15Cl2F3N2O2 (C24 H15 Cl2 F3 N2 O2)

Compound Name

N-[2-chloro-5-(trifluoromethyl)phenyl]-2-{1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide

IUPAC name

N-[2-chloro-5-(trifluoromethyl)phenyl]-2-{1-[(4-chlorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide

SMILES

O=C(C(Nc(cc(C(F)(F)F)cc1)c1Cl)=O)c1cn(Cc(cc2)ccc2Cl)c2c1cccc2

InChI

InChI=1S/C24H15Cl2F3N2O2/c25-16-8-5-14(6-9-16)12-31-13-18(17-3-1-2-4-21(17)31)22(32)23(33)30-20-11-15(24(27,28)29)7-10-19(20)26/h1-11,13H,12H2,(H,30,33)

InChI Key

DCVULZHVFIIZDR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07023043

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.3

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.640

Distribution Coefficient, logD

6.017

Water Solubility, LogSw

-6.40

Polar Surface Area

38.103

Acid Dissociation Constant (pKa)

6.90

Base Dissociation Constant (pKb)

-1.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

8018-1614 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

CORONAVIRUS Library (20774 compounds)

PLpro Library (6343 compounds)

Covalent Inhibitors Library (7986 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Structure:
  • Cyclic compounds
  • 3D
  • Fragments
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 8018-1614 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-1614?
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What is the minimum amount of 8018-1614 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-1614
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-1614
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-1614 available by request