8018-2530 Screening compound: 3-(5-bromo-2-hydroxyphenyl)-5-fluoro-3-hydroxy-1,3-dihydro-2H-indol-2-one

8018-2530 Screening compound: 3-(5-bromo-2-hydroxyphenyl)-5-fluoro-3-hydroxy-1,3-dihydro-2H-indol-2-one
8018-2530 Screening compound: 3-(5-bromo-2-hydroxyphenyl)-5-fluoro-3-hydroxy-1,3-dihydro-2H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-2530
3-(5-bromo-2-hydroxyphenyl)-5-fluoro-3-hydroxy-1,3-dihydro-2H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-2530

Molecular Formula

C14H9BrFNO3 (C14 H9 BrFNO3)

Compound Name

3-(5-bromo-2-hydroxyphenyl)-5-fluoro-3-hydroxy-1,3-dihydro-2H-indol-2-one

IUPAC name

3-(5-bromo-2-hydroxyphenyl)-5-fluoro-3-hydroxy-23-dihydro-1H-indol-2-one

SMILES

OC(c(cc(cc1)F)c1N1)(C1=O)c(cc(cc1)Br)c1O

InChI

InChI=1S/C14H9BrFNO3/c15-7-1-4-12(18)10(5-7)14(20)9-6-8(16)2-3-11(9)17-13(14)19/h1-6,18,20H,(H,17,19)/t14-/m1/s1

InChI Key

NHHARPADRKBDEH-CQSZACIVSA-N

MDL Number (MFCD)

MFCD07657645

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.13

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.642

Distribution Coefficient, logD

3.632

Water Solubility, LogSw

-3.55

Polar Surface Area

56.651

Acid Dissociation Constant (pKa)

9.07

Base Dissociation Constant (pKb)

-0.16

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

7.14

8018-2530 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

DGK Inhibitors Library (10558 compounds)

New Agro Library (44492 compounds)

Opportunistic Pathogens of Immunocompromised Hosts Annotated Library (1773 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 8018-2530 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-2530?
Check Price and Availability of 8018-2530, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-2530 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-2530
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-2530
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-2530 available by request