8018-3126 Screening compound: 3-[2-(4-fluorophenyl)-2-oxoethyl]-1-[(4-fluorophenyl)methyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one

8018-3126 Screening compound: 3-[2-(4-fluorophenyl)-2-oxoethyl]-1-[(4-fluorophenyl)methyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one
8018-3126 Screening compound: 3-[2-(4-fluorophenyl)-2-oxoethyl]-1-[(4-fluorophenyl)methyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-3126
3-[2-(4-fluorophenyl)-2-oxoethyl]-1-[(4-fluorophenyl)methyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-3126

Molecular Formula

C23H17F2NO3 (C23 H17 F2 NO3)

Compound Name

3-[2-(4-fluorophenyl)-2-oxoethyl]-1-[(4-fluorophenyl)methyl]-3-hydroxy-2,3-dihydro-1H-indol-2-one

IUPAC name

3-[2-(4-fluorophenyl)-2-oxoethyl]-1-[(4-fluorophenyl)methyl]-3-hydroxy-23-dihydro-1H-indol-2-one

SMILES

OC(CC(c(cc1)ccc1F)=O)(c(cccc1)c1N1Cc(cc2)ccc2F)C1=O

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.527

Distribution Coefficient, logD

3.527

Water Solubility, LogSw

-3.73

Polar Surface Area

44.043

Acid Dissociation Constant (pKa)

14.32

Base Dissociation Constant (pKb)

-4.55

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

8018-3126 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 8018-3126 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-3126?
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What is the minimum amount of 8018-3126 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-3126
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-3126
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-3126 available by request