8018-4270 Screening compound: 3-(2,4-dichlorophenyl)-6-[2-(4-methoxyphenyl)-4-quinolyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

8018-4270 Screening compound: 3-(2,4-dichlorophenyl)-6-[2-(4-methoxyphenyl)-4-quinolyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
8018-4270 Screening compound: 3-(2,4-dichlorophenyl)-6-[2-(4-methoxyphenyl)-4-quinolyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-4270
3-(2,4-dichlorophenyl)-6-[2-(4-methoxyphenyl)-4-quinolyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-4270

Molecular Formula

C25H15Cl2N5OS (C25 H15 Cl2 N5 OS)

Compound Name

3-(2,4-dichlorophenyl)-6-[2-(4-methoxyphenyl)-4-quinolyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

IUPAC name

4-[3-(24-dichlorophenyl)-[124]triazolo[34-b][134]thiadiazol-6-yl]-2-(4-methoxyphenyl)quinoline

SMILES

COc(cc1)ccc1-c1nc2ccccc2c(-c(s2)nn3c2nnc3-c(ccc(Cl)c2)c2Cl)c1

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

504.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

7.124

Distribution Coefficient, logD

7.122

Water Solubility, LogSw

-6.72

Polar Surface Area

49.325

Acid Dissociation Constant (pKa)

33.29

Base Dissociation Constant (pKb)

5.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.00

8018-4270 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with 8018-4270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-4270?
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What is the minimum amount of 8018-4270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-4270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-4270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-4270 available by request