8018-4618 Screening compound: N'~3~-hydroxy-5-methoxy-1H-indole-3-carboximidamide

8018-4618 Screening compound: N'~3~-hydroxy-5-methoxy-1H-indole-3-carboximidamide
8018-4618 Screening compound: N'~3~-hydroxy-5-methoxy-1H-indole-3-carboximidamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-4618
N'~3~-hydroxy-5-methoxy-1H-indole-3-carboximidamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-4618

Molecular Formula

C10H11N3O2 (C10 H11 N3 O2)

Compound Name

N'~3~-hydroxy-5-methoxy-1H-indole-3-carboximidamide

IUPAC name

(Z)-N'-hydroxy-5-methoxy-1H-indole-3-carboximidamide

SMILES

COc(cc1)cc2c1[nH]cc2/C(/N)=N/O

InChI

InChI=1S/C10H11N3O2/c1-15-6-2-3-9-7(4-6)8(5-12-9)10(11)13-14/h2-5,12,14H,1H3,(H2,11,13)

InChI Key

NFFNHELMHYDQDF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07776715

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

205.22

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.054

Distribution Coefficient, logD

1.049

Water Solubility, LogSw

-2.24

Polar Surface Area

67.408

Acid Dissociation Constant (pKa)

9.49

Base Dissociation Constant (pKb)

4.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

8018-4618 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Fragments Library (11262 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Cardiovascular
Agro:
  • Agro
Targets:
  • Proteases
Structure:
  • Fragments

References: we are preparing a list of scientific research reports with 8018-4618 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-4618?
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What is the minimum amount of 8018-4618 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-4618
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-4618
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-4618 available by request