8018-4850 Screening compound: 4,5-bis(2,5-dimethylthiophen-3-yl)-2-(3,4,5-trimethoxyphenyl)-1H-imidazole

8018-4850 Screening compound: 4,5-bis(2,5-dimethylthiophen-3-yl)-2-(3,4,5-trimethoxyphenyl)-1H-imidazole
8018-4850 Screening compound: 4,5-bis(2,5-dimethylthiophen-3-yl)-2-(3,4,5-trimethoxyphenyl)-1H-imidazole alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-4850
4,5-bis(2,5-dimethylthiophen-3-yl)-2-(3,4,5-trimethoxyphenyl)-1H-imidazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-4850

Molecular Formula

C24H26N2O3S2 (C24 H26 N2 O3 S2)

Compound Name

4,5-bis(2,5-dimethylthiophen-3-yl)-2-(3,4,5-trimethoxyphenyl)-1H-imidazole

IUPAC name

45-bis(25-dimethylthiophen-3-yl)-2-(345-trimethoxyphenyl)-1H-imidazole

SMILES

Cc1cc(-c2c(-c3c(C)sc(C)c3)nc(-c(cc3OC)cc(OC)c3OC)[nH]2)c(C)s1

InChI

InChI=1S/C24H26N2O3S2/c1-12-8-17(14(3)30-12)21-22(18-9-13(2)31-15(18)4)26-24(25-21)16-10-19(27-5)23(29-7)20(11-16)28-6/h8-11H,1-7H3,(H,25,26)

InChI Key

RPGPUTSYNIIOPQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07800080

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.61

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.697

Distribution Coefficient, logD

3.801

Water Solubility, LogSw

-5.83

Polar Surface Area

45.569

Acid Dissociation Constant (pKa)

8.93

Base Dissociation Constant (pKb)

10.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

8018-4850 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with 8018-4850 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-4850?
Check Price and Availability of 8018-4850, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-4850 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-4850
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-4850
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-4850 available by request