8018-5215 Screening compound: 3-(8-methyl-1,2-dihydro-3H-pyrazino[3,2,1-jk]carbazol-3-yl)propanoic acid

8018-5215 Screening compound: 3-(8-methyl-1,2-dihydro-3H-pyrazino[3,2,1-jk]carbazol-3-yl)propanoic acid
8018-5215 Screening compound: 3-(8-methyl-1,2-dihydro-3H-pyrazino[3,2,1-jk]carbazol-3-yl)propanoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-5215
3-(8-methyl-1,2-dihydro-3H-pyrazino[3,2,1-jk]carbazol-3-yl)propanoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-5215

Molecular Formula

C18H18N2O2 (C18 H18 N2 O2)

Compound Name

3-(8-methyl-1,2-dihydro-3H-pyrazino[3,2,1-jk]carbazol-3-yl)propanoic acid

IUPAC name

3-{12-methyl-14-diazatetracyclo[7.6.1.0^{516}.0^{1015}]hexadeca-579(16)10(15)1113-hexaen-4-yl}propanoic acid

SMILES

Cc(cc1)cc(c2ccc3)c1n1c2c3N(CCC(O)=O)CC1

InChI

InChI=1S/C18H18N2O2/c1-12-5-6-15-14(11-12)13-3-2-4-16-18(13)20(15)10-9-19(16)8-7-17(21)22/h2-6,11H,7-10H2,1H3,(H,21,22)

InChI Key

NGYLXHHPDMIGIK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02181912

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

294.35

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.030

Distribution Coefficient, logD

0.360

Water Solubility, LogSw

-3.07

Polar Surface Area

31.581

Acid Dissociation Constant (pKa)

4.05

Base Dissociation Constant (pKb)

10.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

8018-5215 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

DGK Inhibitors Library (10558 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8018-5215 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-5215?
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What is the minimum amount of 8018-5215 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-5215
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-5215
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-5215 available by request