8018-6742 Screening compound: N-(2,6-dimethylphenyl)-2-{1-[(2-fluorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide

8018-6742 Screening compound: N-(2,6-dimethylphenyl)-2-{1-[(2-fluorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide
8018-6742 Screening compound: N-(2,6-dimethylphenyl)-2-{1-[(2-fluorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-6742
N-(2,6-dimethylphenyl)-2-{1-[(2-fluorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-6742

Molecular Formula

C25H21FN2O2 (C25 H21 FN2 O2)

Compound Name

N-(2,6-dimethylphenyl)-2-{1-[(2-fluorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide

IUPAC name

N-(26-dimethylphenyl)-2-{1-[(2-fluorophenyl)methyl]-1H-indol-3-yl}-2-oxoacetamide

SMILES

Cc1cccc(C)c1NC(C(c1cn(Cc(cccc2)c2F)c2c1cccc2)=O)=O

InChI

InChI=1S/C25H21FN2O2/c1-16-8-7-9-17(2)23(16)27-25(30)24(29)20-15-28(22-13-6-4-11-19(20)22)14-18-10-3-5-12-21(18)26/h3-13,15H,14H2,1-2H3,(H,27,30)

InChI Key

ANARLAJMECUEHB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08142374

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.974

Distribution Coefficient, logD

4.974

Water Solubility, LogSw

-4.68

Polar Surface Area

37.405

Acid Dissociation Constant (pKa)

10.71

Base Dissociation Constant (pKb)

1.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

8018-6742 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

CORONAVIRUS Library (20774 compounds)

PLpro Library (6343 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Covalent Inhibitors Library (7986 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with 8018-6742 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-6742?
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What is the minimum amount of 8018-6742 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-6742
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-6742
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-6742 available by request