8018-6832 Screening compound: 5-chloro-2-(3-isoxazolyl)-4,6-dimethylthieno[2,3-b]pyridin-3-amine

8018-6832 Screening compound: 5-chloro-2-(3-isoxazolyl)-4,6-dimethylthieno[2,3-b]pyridin-3-amine
8018-6832 Screening compound: 5-chloro-2-(3-isoxazolyl)-4,6-dimethylthieno[2,3-b]pyridin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-6832
5-chloro-2-(3-isoxazolyl)-4,6-dimethylthieno[2,3-b]pyridin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-6832

Molecular Formula

C12H10ClN3OS (C12 H10 ClN3 OS)

Compound Name

5-chloro-2-(3-isoxazolyl)-4,6-dimethylthieno[2,3-b]pyridin-3-amine

IUPAC name

5-chloro-46-dimethyl-2-(12-oxazol-3-yl)thieno[23-b]pyridin-3-amine

SMILES

Cc1c(c(N)c(-c2nocc2)s2)c2nc(C)c1Cl

InChI

InChI=1S/C12H10ClN3OS/c1-5-8-10(14)11(7-3-4-17-16-7)18-12(8)15-6(2)9(5)13/h3-4H,14H2,1-2H3

InChI Key

GOTACBYSVSZDQA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08142458

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

279.75

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.686

Distribution Coefficient, logD

3.686

Water Solubility, LogSw

-4.23

Polar Surface Area

51.792

Acid Dissociation Constant (pKa)

20.83

Base Dissociation Constant (pKb)

2.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.67

8018-6832 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Fragments Library (11262 compounds)

GABA Library (7115 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Eye
Agro:
  • Agro
  • Agro
Structure:
  • Fragments
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8018-6832 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-6832?
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What is the minimum amount of 8018-6832 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-6832
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-6832
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-6832 available by request