8018-7165 Screening compound: 2,6-difluoro-N-{3-[2-(pyridin-2-yl)ethyl]phenyl}benzamide

8018-7165 Screening compound: 2,6-difluoro-N-{3-[2-(pyridin-2-yl)ethyl]phenyl}benzamide
8018-7165 Screening compound: 2,6-difluoro-N-{3-[2-(pyridin-2-yl)ethyl]phenyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-7165
2,6-difluoro-N-{3-[2-(pyridin-2-yl)ethyl]phenyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-7165

Molecular Formula

C20H16F2N2O (C20 H16 F2 N2 O)

Compound Name

2,6-difluoro-N-{3-[2-(pyridin-2-yl)ethyl]phenyl}benzamide

IUPAC name

26-difluoro-N-{3-[2-(pyridin-2-yl)ethyl]phenyl}benzamide

SMILES

O=C(c(c(F)ccc1)c1F)Nc1cc(CCc2ncccc2)ccc1

InChI

InChI=1S/C20H16F2N2O/c21-17-8-4-9-18(22)19(17)20(25)24-16-7-3-5-14(13-16)10-11-15-6-1-2-12-23-15/h1-9,12-13H,10-11H2,(H,24,25)

InChI Key

QEQQGHVSGZNUKY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08142685

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.36

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.185

Distribution Coefficient, logD

4.172

Water Solubility, LogSw

-4.58

Polar Surface Area

32.601

Acid Dissociation Constant (pKa)

9.55

Base Dissociation Constant (pKb)

5.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

8018-7165 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8018-7165 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-7165?
Check Price and Availability of 8018-7165, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-7165 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-7165
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-7165
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-7165 available by request