8018-7979 Screening compound: 2,4,5-triphenyl-4,5-dihydro-1H-imidazole

8018-7979 Screening compound: 2,4,5-triphenyl-4,5-dihydro-1H-imidazole
8018-7979 Screening compound: 2,4,5-triphenyl-4,5-dihydro-1H-imidazole alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-7979
2,4,5-triphenyl-4,5-dihydro-1H-imidazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-7979

Molecular Formula

C21H18N2 (C21 H18 N2)

Compound Name

2,4,5-triphenyl-4,5-dihydro-1H-imidazole

IUPAC name

(4S5R)-245-triphenyl-45-dihydro-1H-imidazole

SMILES

c1ccc([C@@H]2NC(c3ccccc3)=N[C@@H]2c2ccccc2)cc1

InChI

InChI=1S/C21H18N2/c1-4-10-16(11-5-1)19-20(17-12-6-2-7-13-17)23-21(22-19)18-14-8-3-9-15-18/h1-15,19-20H,(H,22,23)/t19-,20-/m1/s1

InChI Key

UCCFUHZMGXEALP-WOJBJXKFSA-N

MDL Number (MFCD)

MFCD00135903

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

298.39

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

4.944

Distribution Coefficient, logD

4.482

Water Solubility, LogSw

-4.94

Polar Surface Area

22.888

Acid Dissociation Constant (pKa)

11.12

Base Dissociation Constant (pKb)

7.68

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

9.50

8018-7979 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Human Ion Channels Annotated Library (353 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
Agro:
  • Agro
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with 8018-7979 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-7979?
Check Price and Availability of 8018-7979, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-7979 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-7979
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-7979
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-7979 available by request