8018-8270 Screening compound: N-(3-fluoro-2-methylphenyl)-2-oxo-2-(2-phenyl-1H-indol-3-yl)acetamide

8018-8270 Screening compound: N-(3-fluoro-2-methylphenyl)-2-oxo-2-(2-phenyl-1H-indol-3-yl)acetamide
8018-8270 Screening compound: N-(3-fluoro-2-methylphenyl)-2-oxo-2-(2-phenyl-1H-indol-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-8270
N-(3-fluoro-2-methylphenyl)-2-oxo-2-(2-phenyl-1H-indol-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-8270

Molecular Formula

C23H17FN2O2 (C23 H17 FN2 O2)

Compound Name

N-(3-fluoro-2-methylphenyl)-2-oxo-2-(2-phenyl-1H-indol-3-yl)acetamide

IUPAC name

N-(3-fluoro-2-methylphenyl)-2-oxo-2-(2-phenyl-1H-indol-3-yl)acetamide

SMILES

Cc(c(NC(C(c1c(-c2ccccc2)[nH]c2c1cccc2)=O)=O)ccc1)c1F

InChI

InChI=1S/C23H17FN2O2/c1-14-17(24)11-7-13-18(14)26-23(28)22(27)20-16-10-5-6-12-19(16)25-21(20)15-8-3-2-4-9-15/h2-13,25H,1H3,(H,26,28)

InChI Key

BGNHXIHPGZILLU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06668080

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.886

Distribution Coefficient, logD

4.871

Water Solubility, LogSw

-4.94

Polar Surface Area

46.218

Acid Dissociation Constant (pKa)

8.84

Base Dissociation Constant (pKb)

-0.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

8018-8270 in Drug Discovery

Included in Screening Libraries

Covalent Inhibitors Library (7986 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with 8018-8270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-8270?
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What is the minimum amount of 8018-8270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-8270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-8270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-8270 available by request