8018-8693 Screening compound: 6-amino-5-[(dimethylamino)methyl]-1-[(furan-2-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

8018-8693 Screening compound: 6-amino-5-[(dimethylamino)methyl]-1-[(furan-2-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
8018-8693 Screening compound: 6-amino-5-[(dimethylamino)methyl]-1-[(furan-2-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-8693
6-amino-5-[(dimethylamino)methyl]-1-[(furan-2-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-8693

Molecular Formula

C12H16N4O3 (C12 H16 N4 O3)

Compound Name

6-amino-5-[(dimethylamino)methyl]-1-[(furan-2-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-amino-5-[(dimethylamino)methyl]-1-[(furan-2-yl)methyl]-1234-tetrahydropyrimidine-24-dione

SMILES

CN(C)CC(C(N1)=O)=C(N)N(Cc2ccco2)C1=O

InChI

InChI=1S/C12H16N4O3/c1-15(2)7-9-10(13)16(12(18)14-11(9)17)6-8-4-3-5-19-8/h3-5H,6-7,13H2,1-2H3,(H,14,17,18)

InChI Key

JPZXITIRFDAMPU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08445347

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

264.28

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.013

Distribution Coefficient, logD

-0.547

Water Solubility, LogSw

-1.77

Polar Surface Area

72.922

Acid Dissociation Constant (pKa)

10.92

Base Dissociation Constant (pKb)

7.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

8018-8693 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system

References: we are preparing a list of scientific research reports with 8018-8693 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-8693?
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What is the minimum amount of 8018-8693 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-8693
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-8693
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-8693 available by request