8018-8883 Screening compound: N,4,6-trimethyl-N-phenyl-3-(2,4,6-trimethoxybenzamido)thieno[2,3-b]pyridine-2-carboxamide

8018-8883 Screening compound: N,4,6-trimethyl-N-phenyl-3-(2,4,6-trimethoxybenzamido)thieno[2,3-b]pyridine-2-carboxamide
8018-8883 Screening compound: N,4,6-trimethyl-N-phenyl-3-(2,4,6-trimethoxybenzamido)thieno[2,3-b]pyridine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-8883
N,4,6-trimethyl-N-phenyl-3-(2,4,6-trimethoxybenzamido)thieno[2,3-b]pyridine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-8883

Molecular Formula

C27H27N3O5S (C27 H27 N3 O5 S)

Compound Name

N,4,6-trimethyl-N-phenyl-3-(2,4,6-trimethoxybenzamido)thieno[2,3-b]pyridine-2-carboxamide

IUPAC name

N46-trimethyl-N-phenyl-3-(246-trimethoxybenzamido)thieno[23-b]pyridine-2-carboxamide

SMILES

Cc1c(c(NC(c(c(OC)cc(OC)c2)c2OC)=O)c(C(N(C)c2ccccc2)=O)s2)c2nc(C)c1

InChI

InChI=1S/C27H27N3O5S/c1-15-12-16(2)28-26-21(15)23(24(36-26)27(32)30(3)17-10-8-7-9-11-17)29-25(31)22-19(34-5)13-18(33-4)14-20(22)35-6/h7-14H,1-6H3,(H,29,31)

InChI Key

CCGLTENZTVVVML-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09062930

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

505.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.573

Distribution Coefficient, logD

2.085

Water Solubility, LogSw

-4.22

Polar Surface Area

69.635

Acid Dissociation Constant (pKa)

5.93

Base Dissociation Constant (pKb)

3.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

8018-8883 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8018-8883 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-8883?
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What is the minimum amount of 8018-8883 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-8883
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-8883
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-8883 available by request