8018-9240 Screening compound: (2-chlorophenyl)-N-{3-[(E)-2-(4-pyridyl)-1-ethenyl]phenyl}methanesulfonamide

8018-9240 Screening compound: (2-chlorophenyl)-N-{3-[(E)-2-(4-pyridyl)-1-ethenyl]phenyl}methanesulfonamide
8018-9240 Screening compound: (2-chlorophenyl)-N-{3-[(E)-2-(4-pyridyl)-1-ethenyl]phenyl}methanesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-9240
(2-chlorophenyl)-N-{3-[(E)-2-(4-pyridyl)-1-ethenyl]phenyl}methanesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-9240

Molecular Formula

C20H17ClN2O2S (C20 H17 ClN2 O2 S)

Compound Name

(2-chlorophenyl)-N-{3-[(E)-2-(4-pyridyl)-1-ethenyl]phenyl}methanesulfonamide

IUPAC name

1-(2-chlorophenyl)-N-{3-[(1E)-2-(pyridin-4-yl)ethenyl]phenyl}methanesulfonamide

SMILES

O=S(Cc(cccc1)c1Cl)(Nc1cc(/C=C/c2ccncc2)ccc1)=O

InChI

InChI=1S/C20H17ClN2O2S/c21-20-7-2-1-5-18(20)15-26(24,25)23-19-6-3-4-17(14-19)9-8-16-10-12-22-13-11-16/h1-14,23H,15H2

InChI Key

NTCSTZJVKDXEKB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09063055

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.953

Distribution Coefficient, logD

4.920

Water Solubility, LogSw

-5.26

Polar Surface Area

51.672

Acid Dissociation Constant (pKa)

8.50

Base Dissociation Constant (pKb)

1.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

8018-9240 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8018-9240 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-9240?
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What is the minimum amount of 8018-9240 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-9240
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-9240
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-9240 available by request