8018-9473 Screening compound: 2-[5,8-dimethoxy-4-methyl-2-oxo-1(2H)-quinolinyl]acetic acid

8018-9473 Screening compound: 2-[5,8-dimethoxy-4-methyl-2-oxo-1(2H)-quinolinyl]acetic acid
8018-9473 Screening compound: 2-[5,8-dimethoxy-4-methyl-2-oxo-1(2H)-quinolinyl]acetic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-9473
2-[5,8-dimethoxy-4-methyl-2-oxo-1(2H)-quinolinyl]acetic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-9473

Molecular Formula

C14H15NO5 (C14 H15 NO5)

Compound Name

2-[5,8-dimethoxy-4-methyl-2-oxo-1(2H)-quinolinyl]acetic acid

IUPAC name

2-(58-dimethoxy-4-methyl-2-oxo-12-dihydroquinolin-1-yl)acetic acid

SMILES

CC(c(c(OC)ccc1OC)c1N1CC(O)=O)=CC1=O

InChI

InChI=1S/C14H15NO5/c1-8-6-11(16)15(7-12(17)18)14-10(20-3)5-4-9(19-2)13(8)14/h4-6H,7H2,1-3H3,(H,17,18)

InChI Key

AQMQHWYRBAAIET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09063222

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

277.28

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.177

Distribution Coefficient, logD

-3.849

Water Solubility, LogSw

-1.44

Polar Surface Area

60.692

Acid Dissociation Constant (pKa)

3.37

Base Dissociation Constant (pKb)

-4.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.57

8018-9473 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

STING Agonist Library (5895 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with 8018-9473 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-9473?
Check Price and Availability of 8018-9473, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-9473 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-9473
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-9473
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-9473 available by request