8019-0312 Screening compound: 2,4-dichloro-N-{1-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazol-3-yl}-5-sulfamoylbenzamide

8019-0312 Screening compound: 2,4-dichloro-N-{1-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazol-3-yl}-5-sulfamoylbenzamide
8019-0312 Screening compound: 2,4-dichloro-N-{1-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazol-3-yl}-5-sulfamoylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8019-0312
2,4-dichloro-N-{1-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazol-3-yl}-5-sulfamoylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8019-0312

Molecular Formula

C18H15Cl2FN4O3S (C18 H15 Cl2 FN4 O3 S)

Compound Name

2,4-dichloro-N-{1-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazol-3-yl}-5-sulfamoylbenzamide

IUPAC name

24-dichloro-N-{1-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazol-3-yl}-5-sulfamoylbenzamide

SMILES

Cc1cc(NC(c(c(Cl)c2)cc(S(N)(=O)=O)c2Cl)=O)nn1Cc(cc1)ccc1F

InChI

InChI=1S/C18H15Cl2FN4O3S/c1-10-6-17(24-25(10)9-11-2-4-12(21)5-3-11)23-18(26)13-7-16(29(22,27)28)15(20)8-14(13)19/h2-8H,9H2,1H3,(H2,22,27,28)(H,23,24,26)

InChI Key

SYGYWGCKGGFUQS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09063823

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.31

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.132

Distribution Coefficient, logD

0.735

Water Solubility, LogSw

-3.73

Polar Surface Area

88.429

Acid Dissociation Constant (pKa)

5.01

Base Dissociation Constant (pKb)

0.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

8019-0312 in Drug Discovery

Included in Screening Libraries

New Agro Library (44492 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro
Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8019-0312 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8019-0312?
Check Price and Availability of 8019-0312, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8019-0312 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8019-0312
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8019-0312
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8019-0312 available by request