8019-3492 Screening compound: 2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-N-(2-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]formamido}ethyl)acetamide

8019-3492 Screening compound: 2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-N-(2-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]formamido}ethyl)acetamide
8019-3492 Screening compound: 2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-N-(2-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]formamido}ethyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8019-3492
2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-N-(2-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]formamido}ethyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8019-3492

Molecular Formula

C18H18BrFN6O3 (C18 H18 BrFN6 O3)

Compound Name

2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-N-(2-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]formamido}ethyl)acetamide

IUPAC name

2-(4-bromo-35-dimethyl-1H-pyrazol-1-yl)-N-(2-{[3-(4-fluorophenyl)-124-oxadiazol-5-yl]formamido}ethyl)acetamide

SMILES

Cc(n(CC(NCCNC(c1nc(-c(cc2)ccc2F)no1)=O)=O)nc1C)c1Br

InChI

InChI=1S/C18H18BrFN6O3/c1-10-15(19)11(2)26(24-10)9-14(27)21-7-8-22-17(28)18-23-16(25-29-18)12-3-5-13(20)6-4-12/h3-6H,7-9H2,1-2H3,(H,21,27)(H,22,28)

InChI Key

UOGWHGZHXOEJPF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08093999

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.28

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.360

Distribution Coefficient, logD

1.360

Water Solubility, LogSw

-2.24

Polar Surface Area

95.037

Acid Dissociation Constant (pKa)

13.94

Base Dissociation Constant (pKb)

-0.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

8019-3492 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8019-3492 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8019-3492?
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What is the minimum amount of 8019-3492 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8019-3492
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8019-3492
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8019-3492 available by request