8019-4985 Screening compound: 1-[(4-fluorophenyl)methyl]-5-(trifluoromethyl)-1,4-dihydro-1,6-naphthyridin-4-one

8019-4985 Screening compound: 1-[(4-fluorophenyl)methyl]-5-(trifluoromethyl)-1,4-dihydro-1,6-naphthyridin-4-one
8019-4985 Screening compound: 1-[(4-fluorophenyl)methyl]-5-(trifluoromethyl)-1,4-dihydro-1,6-naphthyridin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8019-4985
1-[(4-fluorophenyl)methyl]-5-(trifluoromethyl)-1,4-dihydro-1,6-naphthyridin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8019-4985

Molecular Formula

C16H10F4N2O (C16 H10 F4 N2 O)

Compound Name

1-[(4-fluorophenyl)methyl]-5-(trifluoromethyl)-1,4-dihydro-1,6-naphthyridin-4-one

IUPAC name

1-[(4-fluorophenyl)methyl]-5-(trifluoromethyl)-14-dihydro-16-naphthyridin-4-one

SMILES

O=C1c(c(C(F)(F)F)ncc2)c2N(Cc(cc2)ccc2F)C=C1

InChI

InChI=1S/C16H10F4N2O/c17-11-3-1-10(2-4-11)9-22-8-6-13(23)14-12(22)5-7-21-15(14)16(18,19)20/h1-8H,9H2

InChI Key

FMQRROCSIVEZJL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01244088

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.26

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

2.717

Distribution Coefficient, logD

2.717

Water Solubility, LogSw

-2.94

Polar Surface Area

24.963

Acid Dissociation Constant (pKa)

27.95

Base Dissociation Constant (pKb)

0.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

8019-4985 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Dark Chemical Matter Library (18430 compounds)

Glucocorticoid receptors Library (4806 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Nervous system
Structure:
  • Pool
Targets:
  • Nuclear receptors
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 8019-4985 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8019-4985?
Check Price and Availability of 8019-4985, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8019-4985 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8019-4985
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8019-4985
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8019-4985 available by request