8019-6448 Screening compound: 4-[(6-fluoro-2-methylquinolin-4-yl)amino]benzoic acid

8019-6448 Screening compound: 4-[(6-fluoro-2-methylquinolin-4-yl)amino]benzoic acid
8019-6448 Screening compound: 4-[(6-fluoro-2-methylquinolin-4-yl)amino]benzoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 8019-6448
4-[(6-fluoro-2-methylquinolin-4-yl)amino]benzoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8019-6448

Molecular Formula

C17H13FN2O2 (C17 H13 FN2 O2)

Compound Name

4-[(6-fluoro-2-methylquinolin-4-yl)amino]benzoic acid

IUPAC name

4-[(6-fluoro-2-methylquinolin-4-yl)amino]benzoic acid

SMILES

Cc1cc(Nc(cc2)ccc2C(O)=O)c(cc(cc2)F)c2n1

InChI

InChI=1S/C17H13FN2O2/c1-10-8-16(14-9-12(18)4-7-15(14)19-10)20-13-5-2-11(3-6-13)17(21)22/h2-9H,1H3,(H,19,20)(H,21,22)

InChI Key

RLBRROMGLWTZAR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09028305

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

296.3

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.452

Distribution Coefficient, logD

4.452

Water Solubility, LogSw

-4.21

Polar Surface Area

44.998

Acid Dissociation Constant (pKa)

5.01

Base Dissociation Constant (pKb)

7.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

8019-6448 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

CNS Targets (44014 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 8019-6448 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8019-6448?
Check Price and Availability of 8019-6448, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8019-6448 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8019-6448
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8019-6448
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8019-6448 available by request