8019-6819 Screening compound: 3,5-bis(3,4-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

8019-6819 Screening compound: 3,5-bis(3,4-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
8019-6819 Screening compound: 3,5-bis(3,4-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8019-6819
3,5-bis(3,4-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8019-6819

Molecular Formula

C25H24F3N3O5 (C25 H24 F3 N3 O5)

Compound Name

3,5-bis(3,4-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

IUPAC name

35-bis(34-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine

SMILES

COCc1nn2c(C(F)(F)F)cc(-c(cc3)cc(OC)c3OC)nc2c1-c(cc1)cc(OC)c1OC

InChI

InChI=1S/C25H24F3N3O5/c1-32-13-17-23(15-7-9-19(34-3)21(11-15)36-5)24-29-16(12-22(25(26,27)28)31(24)30-17)14-6-8-18(33-2)20(10-14)35-4/h6-12H,13H2,1-5H3

InChI Key

MGNBJZHPJUZHGA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10038961

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

503.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.236

Distribution Coefficient, logD

4.235

Water Solubility, LogSw

-4.64

Polar Surface Area

58.884

Acid Dissociation Constant (pKa)

28.03

Base Dissociation Constant (pKb)

4.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

8019-6819 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 8019-6819 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8019-6819?
Check Price and Availability of 8019-6819, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8019-6819 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8019-6819
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8019-6819
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8019-6819 available by request