8019-7425 Screening compound: 3-(4-fluorophenyl)-5-[2-(1H-indol-3-yl)ethyl]-4-(2-pyridyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one

8019-7425 Screening compound: 3-(4-fluorophenyl)-5-[2-(1H-indol-3-yl)ethyl]-4-(2-pyridyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one
8019-7425 Screening compound: 3-(4-fluorophenyl)-5-[2-(1H-indol-3-yl)ethyl]-4-(2-pyridyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8019-7425
3-(4-fluorophenyl)-5-[2-(1H-indol-3-yl)ethyl]-4-(2-pyridyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8019-7425

Molecular Formula

C26H20FN5O (C26 H20 FN5 O)

Compound Name

3-(4-fluorophenyl)-5-[2-(1H-indol-3-yl)ethyl]-4-(2-pyridyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one

IUPAC name

3-(4-fluorophenyl)-5-[2-(1H-indol-3-yl)ethyl]-4-(pyridin-2-yl)-1H4H5H6H-pyrrolo[34-c]pyrazol-6-one

SMILES

O=C(c1c2c(-c(cc3)ccc3F)n[nH]1)N(CCc1c[nH]c3c1cccc3)C2c1ncccc1

InChI

InChI=1S/C26H20FN5O/c27-18-10-8-16(9-11-18)23-22-24(31-30-23)26(33)32(25(22)21-7-3-4-13-28-21)14-12-17-15-29-20-6-2-1-5-19(17)20/h1-11,13,15,25,29H,12,14H2,(H,30,31)/t25-/m1/s1

InChI Key

NCOHIRHLIXJATL-RUZDIDTESA-N

MDL Number (MFCD)

MFCD10039300

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.076

Distribution Coefficient, logD

4.075

Water Solubility, LogSw

-4.28

Polar Surface Area

59.036

Acid Dissociation Constant (pKa)

10.77

Base Dissociation Constant (pKb)

1.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

11.54

8019-7425 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with 8019-7425 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8019-7425?
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What is the minimum amount of 8019-7425 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8019-7425
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8019-7425
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8019-7425 available by request