8020-0281 Screening compound: 3-(4-chlorophenyl)-5-(4-methoxyphenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline

8020-0281 Screening compound: 3-(4-chlorophenyl)-5-(4-methoxyphenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline
8020-0281 Screening compound: 3-(4-chlorophenyl)-5-(4-methoxyphenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound 8020-0281
3-(4-chlorophenyl)-5-(4-methoxyphenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8020-0281

Molecular Formula

C28H30ClN3O (C28 H30 ClN3 O)

Compound Name

3-(4-chlorophenyl)-5-(4-methoxyphenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline

IUPAC name

3-(4-chlorophenyl)-5-(4-methoxyphenyl)-7-(2-methylbutan-2-yl)-6H7H8H9H-pyrazolo[15-a]quinazoline

SMILES

CCC(C)(C)C(CC1)Cc2c1n1ncc(-c(cc3)ccc3Cl)c1nc2-c(cc1)ccc1OC

InChI

InChI=1S/C28H30ClN3O/c1-5-28(2,3)20-10-15-25-23(16-20)26(19-8-13-22(33-4)14-9-19)31-27-24(17-30-32(25)27)18-6-11-21(29)12-7-18/h6-9,11-14,17,20H,5,10,15-16H2,1-4H3/t20-/m1/s1

InChI Key

SSSVJYMEKZSSMN-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD12034702

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.02

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.391

Distribution Coefficient, logD

7.391

Water Solubility, LogSw

-6.65

Polar Surface Area

28.479

Acid Dissociation Constant (pKa)

27.33

Base Dissociation Constant (pKb)

-1.56

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.70

8020-0281 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 8020-0281 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8020-0281?
Check Price and Availability of 8020-0281, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8020-0281 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8020-0281
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8020-0281
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8020-0281 available by request