8020-0843 Screening compound: 3-(4-chlorophenyl)-5-(3-fluorophenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline

8020-0843 Screening compound: 3-(4-chlorophenyl)-5-(3-fluorophenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline
8020-0843 Screening compound: 3-(4-chlorophenyl)-5-(3-fluorophenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound 8020-0843
3-(4-chlorophenyl)-5-(3-fluorophenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8020-0843

Molecular Formula

C27H27ClFN3 (C27 H27 ClFN3)

Compound Name

3-(4-chlorophenyl)-5-(3-fluorophenyl)-7-(2-methylbutan-2-yl)-6H,7H,8H,9H-pyrazolo[1,5-a]quinazoline

IUPAC name

3-(4-chlorophenyl)-5-(3-fluorophenyl)-7-(2-methylbutan-2-yl)-6H7H8H9H-pyrazolo[15-a]quinazoline

SMILES

CCC(C)(C)C(CC1)Cc2c1n1ncc(-c(cc3)ccc3Cl)c1nc2-c1cc(F)ccc1

InChI

InChI=1S/C27H27ClFN3/c1-4-27(2,3)19-10-13-24-22(15-19)25(18-6-5-7-21(29)14-18)31-26-23(16-30-32(24)26)17-8-11-20(28)12-9-17/h5-9,11-12,14,16,19H,4,10,13,15H2,1-3H3/t19-/m1/s1

InChI Key

QKXVDWGCJSSAQB-LJQANCHMSA-N

MDL Number (MFCD)

MFCD12034909

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.98

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

7.678

Distribution Coefficient, logD

7.678

Water Solubility, LogSw

-6.76

Polar Surface Area

20.935

Acid Dissociation Constant (pKa)

27.33

Base Dissociation Constant (pKb)

-1.56

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

8020-0843 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with 8020-0843 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8020-0843?
Check Price and Availability of 8020-0843, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8020-0843 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8020-0843
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8020-0843
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8020-0843 available by request