8020-3773 Screening compound: 3,5-bis(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

8020-3773 Screening compound: 3,5-bis(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
8020-3773 Screening compound: 3,5-bis(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8020-3773
3,5-bis(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8020-3773

Molecular Formula

C21H16F3N3O2 (C21 H16 F3 N3 O2)

Compound Name

3,5-bis(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

IUPAC name

35-bis(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine

SMILES

COc(cc1)ccc1-c(cnn1c(C(F)(F)F)c2)c1nc2-c(cc1)ccc1OC

InChI

InChI=1S/C21H16F3N3O2/c1-28-15-7-3-13(4-8-15)17-12-25-27-19(21(22,23)24)11-18(26-20(17)27)14-5-9-16(29-2)10-6-14/h3-12H,1-2H3

InChI Key

MNLYWYMKRZYFSN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD25975467

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.606

Distribution Coefficient, logD

5.606

Water Solubility, LogSw

-5.52

Polar Surface Area

33.984

Acid Dissociation Constant (pKa)

33.29

Base Dissociation Constant (pKb)

3.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

8020-3773 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anti-Inflammatory Library (24602 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 8020-3773 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8020-3773?
Check Price and Availability of 8020-3773, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8020-3773 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8020-3773
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8020-3773
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8020-3773 available by request