8020-4657 Screening compound: 3-(4-fluorophenyl)-7-(pyridin-3-yl)-3H,4H,5H,6H,7H-imidazo[4,5-b]pyridin-5-one

8020-4657 Screening compound: 3-(4-fluorophenyl)-7-(pyridin-3-yl)-3H,4H,5H,6H,7H-imidazo[4,5-b]pyridin-5-one
8020-4657 Screening compound: 3-(4-fluorophenyl)-7-(pyridin-3-yl)-3H,4H,5H,6H,7H-imidazo[4,5-b]pyridin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8020-4657
3-(4-fluorophenyl)-7-(pyridin-3-yl)-3H,4H,5H,6H,7H-imidazo[4,5-b]pyridin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8020-4657

Molecular Formula

C17H13FN4O (C17 H13 FN4 O)

Compound Name

3-(4-fluorophenyl)-7-(pyridin-3-yl)-3H,4H,5H,6H,7H-imidazo[4,5-b]pyridin-5-one

IUPAC name

3-(4-fluorophenyl)-7-(pyridin-3-yl)-3H4H5H6H7H-imidazo[45-b]pyridin-5-one

SMILES

O=C(CC1c2cnccc2)Nc2c1ncn2-c(cc1)ccc1F

InChI

InChI=1S/C17H13FN4O/c18-12-3-5-13(6-4-12)22-10-20-16-14(8-15(23)21-17(16)22)11-2-1-7-19-9-11/h1-7,9-10,14H,8H2,(H,21,23)/t14-/m0/s1

InChI Key

GZFFMFNWYSQUHK-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD16625283

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

308.31

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.142

Distribution Coefficient, logD

2.099

Water Solubility, LogSw

-2.31

Polar Surface Area

46.207

Acid Dissociation Constant (pKa)

12.53

Base Dissociation Constant (pKb)

6.42

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

11.80

8020-4657 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

CNS BBB Library (22607 compounds)

Ion Channels Focused Library (26372 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 8020-4657 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8020-4657?
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What is the minimum amount of 8020-4657 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8020-4657
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8020-4657
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8020-4657 available by request